• Investigación

    El contacto con machos puede reemplazar la inyección degonadotropina coriónica equina (eCG) en cabras lecheras en anestro tratadas con progesterona

    Vol. 20 Núm. 1 (2024)
    Publicado: 2024-08-13
    Lorenzo Álvarez Ramírez
    Universidad Nacional Autónoma de México
    Débora Gamboa Beltrán
    Universidad Nacional Autónoma de México

    Introducción: La gonadotropina coriónica equina (eCG) es un componente crucial de los tratamientos con progestágenos para inducir la actividad reproductiva en cabras. Sin embargo, su uso repetido conduce a la producción de anticuerpos y su origen plantea preocupaciones sobre el bienestar animal. Este estudio comparó el rendimiento reproductivo de cabras lecheras en anestro tratadas con eCG o expuestas a machos después de un tratamiento de progesterona de 14 días. Metodología: Setenta y una cabras en anestro fueron implantadas con un dispositivo de liberación interna controlada (CIDR®) y se colocaron en uno de tres grupos: el grupo eCG (n = 23) recibió una inyección de 200 UI de eCG, el grupo macho (M, n = 24) fue expuesto a un macho en el mismo corral durante un período de 7 días y el grupo control (C, n = 24) no recibió tratamiento adicional. Resultados: Se registraron las tasas de estro, ovulación y embarazo. Las tasas de estro y el intervalo hasta el estro (h±SE) en los grupos eCG (95.7% y 36.4±2.8, respectivamente) y M (95.9%, 48.2 ± 2.7) fueron significativamente diferentes de las del grupo control (58.3%, 62.7 ± 3.6; p<0.05). Las tasas de ovulación fueron más altas en los grupos eCG (91.3%) y M (83.3%) que en el grupo C (29.1%; p<0.05). La tasa de embarazo fue mayor en los grupos eCG (91.3%) y M (79.1%) que en el grupo C (29.1%; p<0.01). Conclusión: Los resultados indican que el efecto macho puede reemplazar a la eCG en cabras en anestro tratadas con progesterona.

    Palabras clave: Bioestimulación , Simulación social, Simulación sexual, Inducción de estro

    Cómo citar

    Álvarez Ramírez, L., & Gamboa Beltrán, D. (2024). El contacto con machos puede reemplazar la inyección degonadotropina coriónica equina (eCG) en cabras lecheras en anestro tratadas con progesterona. Spei Domus, 20(1), 1-14. https://doi.org/10.16925/2382-4247.2024.01.03

    Fatet A, Pellicer-Rubio MT, Leboeuf B. Reproductive cycle of goats. Anim Reprod Sci. 2011;124(3–4):211–219. https://doi.org/10.1016/j.anireprosci.2010.08.029

    Alvarez L. Aspectos de comportamiento y bioestimulación sexual en caprinos. In: XX Reunión Nacional sobre Caprinocultura. Culiacán, Sinaloa, México; 2005, pp. 39–58

    Simões J. Recent advances on synchronization of ovulation in goats, out of season, for a more sustainable production. Asian Pacific J Reprod. 2015;4(2):157–165. https://doi.org/10.1016/S2305-0500(15)30014-2

    Habeeb HMH, Kutzler AM. Estrus synchronization in the sheep and goat. Vet Clin North Am - Food Anim Pract. 2021;37(1):125–137. https://doi.org/10.1016/j.cvfa.2020.10.007

    Omontese BO, Rekwot PI, Ate IU, Ayo JO, Kawu MU, Rwuaan JS, Nwannenna AI, Mustapha RA, Bello, AA. An update on oestrus synchronisation of goats in Nigeria. Asian Pacific J Reprod. 2016;5(2):96–101. https://doi.org/10.1016/j.apjr.2016.01.002

    Umberger SH, Jabbar G, Lewis GS. Seasonally anovulatory ewes fail to respond to progestogen treatment in the absence of gonadotropin stimulation. Theriogenology. 1994;42(8):1329–1336. https://doi.org/10.1016/0093-691X(94)90253-F

    Barrett DMW, Bartlewski PM, Batista-Arteaga M, Symington A, Rawlings NC. Ultrasound and endocrine evaluation of the ovarian response to a single dose of 500 IU of eCG following a 12-day treatment with progestogen-releasing intravaginal sponges in the breeding and nonbreeding seasons in ewes. Theriogenology. 2004;61(2–3):311–327. doi: https://doi.org/10.1016/S0093-691X(03)00215-2

    de Andrade ABP, Morais MCC, Rangel PSC, Oliveira MEF, Souza-Fabjan JMG, Fonseca JF. Effect of eCG in a short-term synchronization treatment on ovarian status, estrus synchrony, and ovulation in dairy goats managed under tropical conditions. Trop Anim Health Prod. 2021;53(2). https://doi.org/10.1007/s11250-021-02699-y

    Sharif B, Hassan M, Arshad U, Tahir MZ, Ahmad E, Khan MI, Shazad M, Mohsin I, Sosa F, Rehman A. Effect of eCG dose on ovarian haemodynamics, hormonal profiles and prolificacy rate when oestrus was induced during low-breeding season in Beetal goats. Reprod Domest Anim. 2023;58(1):48–59. https://doi.org/10.1111/rda.14257

    Bryan MA, Bó G, Mapletoft RJ, Emslie FR. The use of equine chorionic gonadotropin in the treatment of anestrous dairy cows in gonadotropin-releasing hormone/progesterone protocols of 6 or 7 days. J Dairy Sci. 2013;96(1):122–131. https://doi.org/10.3168/jds.2012-5452

    Teixeira ACB, Valle GR, Riveros JAN, Diniz JHW, Wenceslau RR, Monteiro GA, et al. Effects of equine chorionic gonadotropin on ovulatory and luteal characteristics of mares submitted to an P4-based protocol of ovulation induction with hCG. J Equine Vet Sci. 2020;94:103233. https://doi.org/10.1016/j.jevs.2020.103233

    Abecia JA, Forcada F, González-Bulnes A. Hormonal control of reproduction in small ruminants. Anim Reprod Sci. 2012;130(3–4):173–179. https://doi.org/10.1016/j.anireprosci.2012.01.011

    Manteca Vilanova X, De Briyne N, Beaver B, Turner PV. Horse welfare during equine chorionic gonadotropin (eCG) production. Animals. 2019;9(12):1053. https://doi.org/10.3390/ani9121053

    Bodin L, Drion PV, Remy B, Brice G, Cognié Y, Beckers JF. Anti-PMSG antibody levels in sheep subjected annually to oestrus synchronisation. Reprod Nutr Dev. 1997;37(6):651–660.

    Drion PV, Furtoss V, Baril G, Manfredi E, Bouvier F, Pougnard JL, Bernelas D, Caugnon P, McNamara E, Remy B, Sulon J, Becjers JF, Bodin L, Leboeuf B. Four years of induction/synchronization of estrus in dairy goats: effect on the evolution of eCG binding rate in relation with the parameters of reproduction. Reprod Nutr Dev. 2001;41(5):401–412. https://doi.org/10.1051/rnd:2001140

    Hervé V, Roy F, Bertin J, Guillou F, Maurel MC. Antiequine chorionic gonadotropin (eCG) antibodies generated in goats treated with eCG for the induction of ovulation modulate the luteinizing hormone and follicle-stimulating hormone bioactivities of eCG differently. Endocrinology. 2004;145(1):294–303. https://doi.org/10.1210/en.2003-0595

    Maurel MC, Roy F, Hervé V, Bertin J, Vaiman D, Cribiu E, Manfredi E, Bouvier F, Boue P, Guillou F. Réponse immunitaire à la eCG utilisée dans le traitement de l’induction d’ovulation chez la chèvre et la brebis. Gynecol Obstet Fertil. 2003;31(9):766–769. https://doi.org/10.1016/S1297-9589(03)00214-5

    Roy F, Combes B, Vaiman D, Cribiu EP, Pobel T, Delétang F, Combarnous Y, Guillou F, Maurel MC. Humoral immune response to equine chorionic gonadotropin in ewes: Association with major histocompatibility complex and interference with subsequent fertility. Biol Reprod. 1999;61(1):209–218. https://doi.org/10.1095/biolreprod61.1.209

    Roy F, Maurel MC, Combes B, Vaiman D, Cribiu EP, Lantier I, Pobel T, Delétang F, Combarnous Y, Guillou F. The negative effect of repeated equine chorionic gonadotropin treatment on subsequent fertility in alpine goats is due to a humoral immune response involving the major histocompatibility complex. Biol Reprod. 1999;60(4):805–813. https://doi.org/10.1095/biolreprod60.4.805

    Hashem NM, El-Hawy AS, El-Bassiony MF, El-Hamid ISA, Gonzalez-Bulnes A, Martinez-Ros P. Use of GnRH-encapsulated chitosan nanoparticles as an alternative to eCG for induction of estrus and ovulation during non-breeding season in sheep. Biology (Basel). 2023;12(3):351. https://doi.org/10.3390/biology12030351

    Alvarez L, Zarco LA. Los fenómenos de bioestimulación sexual en ovejas y cabras. Vet México. 2001;32(2):117–129.

    Delgadillo JA, Flores JA, Duarte G, Vielma J, Hernández H, Bedos M, Fitz G, Fernández IG, López-Sebastián A, Gómez-Brunet A, Santiago-Moreno J, Zaragoza LA, Keller M, Chemineau P. Out-of-season control of reproduction in subtropical goats without exogenous hormonal treatments. Small Rumin Res. 2014;121(1):7–11. https://doi.org/10.1016/j.smallrumres.2014.01.011

    Pellicer-Rubio MT, Leboeuf B, Bernelas D, Forgerit Y, Pougnard JL, Bonné JL, Senty E, Breton F, Brun F, Chemineau P. High fertility using artificial insemination during deep anoestrus after induction and synchronisation of ovulatory activity by the “male effect” in lactating goats subjected to treatment with artificial long days and progestagens. Anim Reprod Sci. 2008;109(1–4):172–188. https://doi.org/10.1016/j.anireprosci.2007.11.026

    Pellicer-Rubio MT, Leboeuf B, Bernelas D, Forgerit Y, Pougnard JL, Bonné JL, Senty E, Chemineau P. Highly synchronous and fertile reproductive activity induced by the male effect during deep anoestrus in lactating goats subjected to treatment with artificially long days followed by a natural photoperiod. Anim Reprod Sci. 2007;98(3–4):241–258. https://doi.org/10.1016/j.anireprosci.2006.03.002

    Guillen-Muñoz JM, Meza-Herrera CA, Rivas-Muñoz R, Zuñiga-Garcia Z, Calderon-Leyva G, Mellado M, Veliz-Deras F. The use of female estrogenized goats as sexual stimulator of crossbred dairy males subsequently exposed to acyclic goats during two phases of the anestrous season. Theriogenology. 2018;119:175–182. https://doi.org/10.1016/j.theriogenology.2018.07.003

    Walkden-Brown SW, Restall BJ, Norton BW, Scaramuzzi RJ. The “female effect” in Australian cashmere goats: Effect of season and quality of diet on the LH and testosterone response of bucks to oestrous does. J Reprod Fertil. 1994;100(2):521–531. https://doi.org/10.1530/jrf.0.1000521

    De Castro T, Rubianes E, Menchaca A, Rivero A. Ovarian dynamics, serum estradiol and progesterone concentrations during the interovulatory interval in goats. Theriogenology. 1999;52(3):399–411. https://doi.org/10.1016/S0093-691X(99)00138-7

    SAS. SAS/STAT(R) 9.3 user´s guide. 2024. https://support.sas.com/documentation/cdl/en/statug/63962/HTML/default/viewer.htm#statug_glm_sect007.htm.

    Abecia JA, Forcada F, González-Bulnes A. Pharmaceutical control of reproduction in sheep and goats. Vet Clin North Am - Food Anim Pract. 2011;27(1):67–79. https://doi.org/10.1016/j.cvfa.2010.10.001

    Landaeta-Hernández AJ, Ungerfeld R, Chenoweth PJ. Biostimulation and pheromones in livestock: A review. Anim Reprod Sci. 2023;248:107154. https://doi.org/10.1016/j.anireprosci.2022.107154

    Freitas VJF, Rondina D, Lopes Júnior ES, Teixeira DIA, Paula NRO. Hormonal treatments for the synchronisation of oestrus in dairy goats raised in the tropics. Reprod Fertil Dev. 2004;16(4):415–420. https://doi.org/10.1071/RD04031

    Romano JE. Does in proestrus-estrus hasten estrus onset in does estrous synchronized during breeding season. Appl Anim Behav Sci. 2002;77(4):329–334. https://doi.org/10.1016/S0168-1591(02)00064-3

    Mellado M, Olivas R, Ruiz F. Effect of buck stimulus on mature and pre-pubertal norges-tomet-treated goats. Small Rumin Res. 2000;36(3):269–274. https://doi.org/10.1016/S0921-4488(99)00122-4

    Nakafeero A, Hassen A, Lehloenya KC. Investigation of ram effect and eCG usage in progesterone based oestrous synchronization protocols on fertility of ewes following fixed time artificial insemination. Small Rumin Res. 2020;183:106034. https://doi.org/10.1016/j.smallrumres.2019.106034

    Contreras-Solis I, Vasquez B, Diaz T, Letelier C, Lopez-Sebastian A, Gonzalez-Bulnes A. Efficiency of estrous synchronization in tropical sheep by combining short-interval clopros-tenol-based protocols and “male effect.” Theriogenology. 2009;71(6):1018–1025. https://doi.org/10.1016/j.theriogenology.2008.11.004

    Ungerfeld R. Combination of the ram effect with PGF2α estrous synchronization treatments in ewes during the breeding season. Anim Reprod Sci. 2011;124(1–2):65–68. https://doi.org/10.1016/j.anireprosci.2011.02.021

    Alvarez L, Ducoing A, Zarco L, Trujillo A. Conducta estral, concentraciones de LH y función lútea en cabras en anestro estacional inducidas a ciclar mediante el contacto con cabras en estro. Vet México. 1999;30(1):25–31.

    Rodríguez-Martínez R, Ángel-García O, Guillén-Muñoz JM, Robles-Trillo PA, De Santiago-Miramontes M de los A, Meza-Herrera CA, Mellado M, Véliz FG. Estrus induction in anestrous mixed-breed goats using the “female-to-female effect.” Trop Anim Health Prod. 2013;45(4):911–915. https://doi.org/10.1007/s11250-012-0305-z

    Martin GB, Milton JTB, Davidson RH, Banchero Hunzicker GE, Lindsay DR, Blache D. Natural methods for increasing reproductive efficiency in small ruminants. Anim Reprod Sci. 2004;82–83:231–245. https://doi.org/10.1016/j.anireprosci.2004.05.014

    Baril G, Remy B, Leboeuf B, Beckers JF, Saumande J. Synchronization of estrus in goats: The relationship between eCG binding in plasma, time of occurrence of estrus and fertility following artificial insemination. Theriogenology. 1996;45(8):1553–1559. https://doi.org/10.1016/0093-691X(96)00123-9

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