Study of coronary sinus and its tributaries in pigs
Introduction. Similarities between the bodies of pigs and humans have encouraged studies in comparative anatomy, trying to describe in detail the anatomical variations that could influence in the xenotransplantation, given that advances in genetics, immunology and biotechnology are large, this possibility is not far. The objective of this work was to make contributions to the vascular study of porcine heart.
Methodology. 60 porcine hearts, with an average of 5 months old and weighing 85-95kg were obtained from plant Vijagual. After receipt hearts were kept in water for 6 hours, then they were perfused with polyester resin semi-synthetic and mineral blue color, moreover the left coronary artery was perfused with red mineral color. Subsequently, the hearts were subjected to a process of partial corrosion with potassium hydroxide (15%), then the coronary sinus and its tributary branches were dissected from its origin to its distal segments, path, shapes, sizes, anastomosis and presence of registered anatomical variations. Photographic record of the samples was performed.
Results. The distal caliber of Great cardiac vein (5.36 +/- 1,04mm), its origin was determined from the apex at 70% of anatomical pieces it studied was determined and the ventricular groove paraconal 30% of the pieces analyzed. The arteriovenous trigone was found in 58 of cardiac structures studied (96.66%).
Conclusion. The description of the anatomic variations present in the pig heart structure will contribute to the possibility of xenotransplantation and also provides data for the development of studies on cardiovascular surgery and certain diseases of clinical and epidemiological importance.
Cómo citar
Licencia
En calidad de autor del artículo, declaro que este, es un trabajo original, inédito, de mi creación exclusiva, que no se ha postulado a evaluación simultánea en otra publicación y que no cuenta con algún impedimento de cualquier naturaleza para la concesión de los derechos previstos en este contrato.
En ese sentido, me comprometo a esperar un resultado de evaluación de la revista, antes de considerar su presentación a otro medio, en caso de que la respuesta de publicación no sea positiva; adicionalmente, me comprometo a responder por cualquier acción de reivindicación, plagio u otra clase de reclamación que al respecto pudiera sobrevivir por parte de terceros.
Asimismo, declaro que como autor o coautor, estoy de acuerdo por completo con los contenidos presentados en este trabajo y cedo todos los derechos patrimoniales, es decir, la reproducción, comunicación pública, distribución, divulgación, transformación, puesta a disposición y demás formas de explotación de la obra por cualquier medio o procedimiento, a la revista y a la Editorial de la Universidad Cooperativa de Colombia.
Crick SJ, Sheppard MN, Ho SY, Gebstein L, Anderson RH. Anatomy of the pig heart: comparisons with normal human cardiac structure. J Anat. 1998;193 ( Pt 1:105-119. doi:10.1046/j.1469-7580.1998.19310105.x.
Huang AH, Dorsey LM a., Guyton R a. Hemodynamic significance of the coronary vein valves. Ann Thorac Surg. 1994;57(2):424-430. doi:10.1016/0003-4975(94)91009-X.
Swindle MM, Medicine C. Technical Bulletin Comparative Anatomy of the Pig ( cont ’ d ). :1-3.
Sahni D, Kaur GD, Jit H, Jit I. Anatomy & distribution of coronary arteries in pig in comparison with man. Indian J Med Res. 2008;127(6):564-570. http://www.ncbi.nlm.nih.gov/pubmed/18765875.
Ortale JR, Gabriel E a, Iost C, Márquez CQ. The anatomy of the coronary sinus and its tributaries. Surg Radiol Anat. 2001;23(1):15-21. http://www.ncbi.nlm.nih.gov/pubmed/11370136.
Singh JP, Houser S, Heist EK, Ruskin JN. The coronary venous anatomy: a segmental approach to aid cardiac resynchronization therapy. J Am Coll Cardiol. 2005;46(1):68-74. doi:10.1016/j.jacc.2005.04.017.
Gilard M, Mansourati J. Angiographic anatomy of the coronary sinus and its tributaries. Pacing Clin …. 1998;21:2280-2284. http://onlinelibrary.wiley.com/doi/10.1111/j.1540-8159.1998.tb01167.x/full. Accessed June 18, 2014.
Schaffler GJ, Groell R, Peichel KH, Rienmüller R. Imaging the coronary venous drainage system using electron-beam CT. Surg Radiol Anat. 2000;22(1):35-39. http://www.ncbi.nlm.nih.gov/pubmed/10863745.
Pontone G, Andreini D, Cortinovis S, et al. Imaging of cardiac venous system in patients with dilated cardiomyopathy by 64-slice computed tomography: comparison between non-ischemic and ischemic etiology. Int J Cardiol. 2010;144(2):340-343. doi:10.1016/j.ijcard.2009.03.043.
Kato T, Yasue T, Yoshitami S, et al. Angiographic diference in coronary artery of man, doc, pig, and monkey. Acta pathol Jpn. 1987;37(3):361-373.
Sousa-Rodrigues CF, Alcântara SF., Silva WNV., Alcântara SF, Olave E. Trígono arterio-venoso del corazón. Int J Morphol. 2004;22(4):291-296.
Loukas M, Bilinsky S, Bilinsky E, el-Sedfy A, Anderson RH. Cardiac veins: a review of the literature. Clin Anat. 2009;22(1):129-145. doi:10.1002/ca.20745.
Kaczmarek M, Czerwiński F. Assessment of the course of the great cardiac vein in a selected number of human hearts. Folia Morphol (Warsz). 2007;66(3):190-193. http://www.ncbi.nlm.nih.gov/pubmed/17985317.
Indmedica - Journal of the Anatomical Society of India.
Gómez FA, Ballesteros LE, Cortés LS. Morphologic description of great cardiac vein in pigs compared to human hearts. Rev Bras Cir Cardiovasc. 2014:63-69. doi:10.5935/1678-9741.20140101.
Maros TN, Racz L, Plugor S, Maros TG. Contributions to the morphology of the human coronary sinus. Anat Anz. 1983;154(2):133-144.
Van de Veire NR, Schuijf JD, De Sutter J, et al. Non-invasive visualization of the cardiac venous system in coronary artery disease patients using 64-slice computed tomography. J Am Coll Cardiol. 2006;48(9):1832-1838. doi:10.1016/j.jacc.2006.07.042.
