Andamios de quitosano con L-Arginina para su aplicación en salud dental

Santiago Herrera Guardiola; Mayra Eliana Valencia Zapata

doi:10.16925/2357-4607.2021.02.07

Enxerto L-arginina para á aplicação na Saúde Oral

Artículos de revisión

https://doi.org/10.16925/2357-4607.2021.02.07

Santiago Herrera Guardiola Ver Biografía

Universidad del Valle

Mayra Eliana Valencia Zapata Ver Biografía

Universidad Del Valle

Atualmente, os scaffolds são utilizados na saúde para fornecer suporte estrutural aos tecidos, orientar o cres-cimento celular, controlar colônias bacterianas e promover processos metabólicos. Vários métodos de con-formação têm sido propostos e, dependendo de suas características físicas, podem ser aplicados a diferentes abordagens na área da saúde. A revisão a seguir ilustra como os avanços nos scaffolds de quitosana influen-ciaram o campo da bioengenharia e da saúde, sua relação com aminoácidos, métodos de produção de hidrogel e quais seriam seus principais benefícios para a terapêutica de acordo com os objetivos do tratamento. Foi realizada uma revisão nas bases de dados Scopus e Web of Science e foram considerados 23 artigos originais de pesquisas in vitro, modelos animais, coortes e ensaios clínicos randomizados. Conclui-se que os scaffolds de quitosana são propícios para serem utilizados em tecidos e, dependendo do seu grau de desacetilação e peso molecular, podem ser úteis para diferentes objetivos biológicos. Não há protocolo estabelecido e não foi possível encontrar uma relação efetiva entre o peso molecular ou seu grau de desacetilação com a função biológica a ser avaliada. Mais pesquisas são necessárias para poder aplicá-lo às diferentes especialidades odontológicas.

Palavras-chave: quitosana, scaffolds teciduais, arginina, odontologia, hidrogéis

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Enxerto L-arginina para á aplicação na Saúde Oral. (2021). Revista Nacional De Odontología, 17(2), 1-21. https://doi.org/10.16925/2357-4607.2021.02.07

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v. 17 n. 2 (2021)

Publicado

2021-07-12

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Enxerto L-arginina para á aplicação na Saúde Oral. (2021). Revista Nacional De Odontología, 17(2), 1-21. https://doi.org/10.16925/2357-4607.2021.02.07

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