Case Report

Pleomorphic adenoma vs benign lymphoepithelial cyst

Clinical and histopathological diagnosis

Vol. 16 No. 2 (2020)
Published: 2020-11-15
Samuel E. Urbano Del Valle
Eilien G. Tovío Martínez
Shanny L. Miranda Duncan
Jonathan Harris Ricardo

Introduction: the pleomorphic adenoma is the neoplasm with the highest incidence of salivary glands, representing around 3-10% of the tumors of the head region; the benign lymphoepithelial lesion, on the other hand, has been widely recognized as a common cause of enlarged parotid gland in patients usually infected with HIV. The cystic lesions of the parotid gland are rare, characterized by being slow-growing, asymptomatic tumors of firm consistency and covered by healthy skin or mucosa.

Objective: to describe the histological, clinical and imaging characteristics, which must be carried out in a multidisciplinary manner, in order to carry out an appropriate and accurate treatment plan for the pathology.

Clinical case: male patient attending the clinic due to asymptomatic tumor lesion located in the right preauricular region. Magnetic resonance of the area is sent confirming the lesion, a surgical approach is made to eliminate the injury and compromised tissues, subsequently, histological study confirms the diagnosis of pleomorphic adenoma.

Conclusion: Although surgical intervention is the treatment of choice for both, the pleomorphic adenoma and the benign lymphoepithelial lesion, it is imperative to perform an exhaustive clinical, imaging and histopathological study of the possible lesion, thus ruling out other entities that require a treatment plan totally different, avoiding mistake.

Keywords: Array, Array, Array, Array, Array, Array

How to Cite

Pleomorphic adenoma vs benign lymphoepithelial cyst: Clinical and histopathological diagnosis. (2020). Revista Nacional de Odontología, 16(2), 1-13. https://doi.org/10.16925/2357-4607.2020.02.12

(1) Alves V, Pérez M, de Castro J, Vieira C, Leão J, Perez D. Intraoral Pleomorphic Adenoma in Young Patients. Journal of Craniofacial Surgery. 2018; 29(2): e209-e211.

(2) Pillai S, Agarwal AC, Mangalore AB, Ramaswamy B, Shetty S. Benign Lymphoepithelial Cyst of the Parotid in HIV Negative Patient. J Clin Diagn Res. 2016;10(4): MD05-MD06.

(3) Álvarez E, Botero X, Ardila M. Adenoma pleomórfico benigno del paladar: presentación de un caso. AMC. 2013; 17(4): 497-505.

(4) Ahamed A, Kannan V, Velaven K, Sathyanarayanan G, Roshni J, Elavarasi E. Lymphoepithelial cyst of the submandibular gland. J Pharm Bioallied Sci. 2014; 6(Suppl 1): S185-S187.

(5) Singh A, Kumar N, Sharma P, Singh S. Pleomorphic adenoma involving minor salivary glands of upper lip: A rare phenomenon. Journal of cancer research and therapeutics. 2015; 11(4): 1025.

(6) Sánchez J, Franco L, Ochoa J. Adenoma pleomorfo de la glándula Parótida tratados quirúrgicamente, experiencia de 7 años. Archivos del Hospital Universitario" General Calixto García". 2019; 7(1): 28-32.

(7) Castañeda A, Hernández M. Lesión linfoepitelial benigna relacionada con el VIH en un paciente pediátrico: informe de un caso. Anales de Radiología, México. 2019; 17(4): 293-301.

(8) Tarsitano A, Pizzigallo A, Giorgini F, Marchetti C. Giant pleomorphic adenoma of the parotid gland: an unusual case presentation and literature review. Acta Otorrinolaringol Ital. 2015; 35(4): 293-296.

(9) Valstar M, De Ridder M, Van Den Broek EC, Stuiver MM, Van Dijk BAC, Van Velthuysen LF, et al. Salivary gland pleomorphic adenoma in the Netherlands: A nationwide obserational study of primary tumor incidence, malignant transformation, recurrence, and risk factors for recurrence. Oral Oncol. 2017; 66: 93-99.

(10) Joshi J, Shah S, Agarwal D, Khasgiwal A. Benign lymphoepithelial cyst of parotid gland: Review and case report. J Oral Maxillofac Pathol. 2018; 22(Suppl 1): S91-S97.

(11) Enescu A, Enescu A, Bălăşoiu, M, Ciolofan M, Cápitanescu A. Histopathological study of pleomorphic adenoma of salivary glands. Rom J Morphol Embryol. 2014; 55(3): 1149-1153.

(12) Khan M, Raza SS, Zaidi SAH, Hussain AK, Nadeem MD, Farid K. Pleomorphic adenoma of minor salivary glands. J Ayub Med Coll Abbottabad. 2016; 28(3): 620–622.

(13) Basu S. y Patra T. Pleomorphic Adenoma of Submandibular gland. Journal of Case Reports. 2018;8(2):98-101.

(14) Yáñez R, Loyola F, Maíz C, Mariangel P, Cornejo J, Martínez R, et al. tratamiento quirúrgico de los tumores de parótida: experiencia de 10 años. Revista Chilena de Cirugía. 2014; 66(3): 245-250

(15) Uz U, Celik O. Pleomorphic Adenoma of the Posterior Surface of the Soft Palate Causing Sleep Disturbance: A Case Report. Am J Case Rep. 2017; 18: 1266-1270.

(16) Koyama M, Terauchi T, Koizumu M, Tanaka H, Sato Y. Metastasizing pleomorphic adenoma in the multiple organs: A case report on FDG-PET/CT imaging. Medicine (Baltimore). 2018; 97(23): e11077.

(17) Velpula N, Annam SR, Pallepati SR, Kumar R, Kumar A. Pleomorphic Adenoma of Cheek Masquerading as Fibrolipoma - Case Report with Review. J Clin Diagn Res. 2015; 9(11): ZD13- ZD15.

(18) Mukai H, Motoori K, Horikoshi T, Takshima H, Nagai Y, Okamoto Y, et al. Adenoma de células basales de la glándula parótida; Características de la RM y diferenciación del adenoma pleomórfico. Dentomaxillofac Radiol. 2016; 45(4): 20150322.

(19) Gallana S, Mayorga F, Herce J, Díaz M. Adenoma pleomorfo intraoral. Revista Española de Cirugía Oral y Maxilofacial. 2006; 28(1): 63-66.

(20) Jain S, Hasan S, Vyas N, Shah N, Dalal S. Pleomorphic Adenoma of the Parotid Gland: Report of a Case With Review of Literature. Ethiop J Health Sci. 2015; 25(2): 189–194.

MÉTRICAS
ARTICLE VIEWS: 1030
PDF VIEWS: 1241

Most read articles by the same author(s)