Resistencia bacteriana a los antibióticos: mecanismos de transferencia

Pilar Sánchez-B.; Rafael Muñoz-M.; Norma P. Gutiérrez-M.

Bacterial Resistance to Antibiotics: Mechanisms of Transfer : Mechanisms of Transfer

Revisión

Pilar Sánchez-B. Ver Biografía

Universidad Cooperativa de Colombia

Rafael Muñoz-M. Ver Biografía

Universidad Cooperativa de Colombia

Norma P. Gutiérrez-M. Ver Biografía

Universidad Cooperativa de Colombia

Antimicrobial resistance bacteria have drawn the interest of researches because their adaptive ability has hampered treatment and therefore, the eradication of diseases that stem from their pathogenic action. This was observed soon after the successful beginning of pharmacological therapy around the world that later proved to be inefficient. This is currently a challenge for science. Continuing study of antimicrobial resistance has made it possible to understand how bacteria can overcome therapeutic strategy by means of genetic transference. Diverse mechanisms have been identified for transferring resistance between bacterium of the same species and different species through exchanges of genes that imply the participation of elements such as plasmids, sequence insertion, integrons, transposons and bacteriophages. These permit gene recombination, where genetic elements with two different origins come together in one unit, through such mechanisms as transformation, transduction and conjugation. This review discusses the three transfer mechanisms mentioned above and the participation of genetic exchange elements for the transfer of bacterial resistance to antibiotics with the aim of facilitating understanding of the processes of defense of these microorganisms that directly or indirectly affect animal and human health.

Keywords: bactheriophage, bacterial genome, integrons, transposons

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Sánchez-B., P., Muñoz-M., R., & Gutiérrez-M., N. P. (2012). Bacterial Resistance to Antibiotics: Mechanisms of Transfer: Mechanisms of Transfer. Spei Domus, 8(17). https://revistas.ucc.edu.co/index.php/sp/article/view/94

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Vol. 8 No. 17 (2012)

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