Efectos teratogénicos de insecticidas organofosforados en la etiología de labio y paladar hendido: revisión de literatura

Contenido principal del artículo

Jesús Gabriel Ortega-Miller
Salomón Yezioro-Rubinsky
Berta Cecilia Benavides-Pinto
Liliana Carolina Báez-Quintero

Resumen

Introducción:el objetivo fue revisar la evidencia científica sobre la asociación entre la exposición de individuos a insecticidas organofosforados, con la prevalencia de labio y paladar fisurado no sindrómico. Materiales y Métodos: se realizaron búsquedas de artículos científicos en las bases de datos Pubmed, Science Direct, Google Académico, Medline, Cochrane y Scielo, publicados entre los años 2000 a 2015. Se buscaron artículos teniendo en cuenta los términos MESH, incluyendo estudios de revisión de literatura, metanalisis, casos y controles, y experimentales in vivo, excluyéndose estudios experimentales in vitro, encontrándose 25 artículos que cumplieron con los criterios de inclusión. Resultados: un significativo número de estudios establecieron una asociación entre la exposición a insecticidas órganofosforados con efectos teratogénicos relacionados con la formación del labio y paladar hendido; estudios experimentales in vivo en animales relacionaron la exposición al Insecticida Organofosforado Clorpirifos, con mayor prevalencia de paladar hendido.Conclusión:Los resultados de la  presente revisión de literatura no encontró asociación entre  la exposición a Insecticidas Organofosforados y  efectos teratogénicos relacionados con la formación del labio y paladar hendido.

Detalles del artículo

Cómo citar
Ortega-Miller, J. G., Yezioro-Rubinsky, S., Benavides-Pinto, B. C., & Báez-Quintero, L. C. (2017). Efectos teratogénicos de insecticidas organofosforados en la etiología de labio y paladar hendido: revisión de literatura. Revista Nacional De Odontología, 13(24). https://doi.org/10.16925/od.v12i24.1658
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Revisión de Tema
Biografía del autor/a

Jesús Gabriel Ortega-Miller, Facultad de Odontología, Universidad Nacional de Colombia.

Odontólogo.

Salomón Yezioro-Rubinsky, Facultad de Odontología, Universidad Nacional de Colombia.

Especialista.

Berta Cecilia Benavides-Pinto, Universidad Cooperativa de Colombia.

Magister.

Liliana Carolina Báez-Quintero, Universidad Estadual Paulista, Câmpus de Araçatuba, São Paulo Brasil.

Magister.

Citas

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