Uso de CLAR en fase inversa para la determinación del contenido de formaldehído libre en esmaltes de uñas

María Maldonado Santoyo; Erika Hernández Guerrero; Gladys Morales López; Javier Antonio Arcibar Orozco; Juliette Alexandra Lambert; Jennifer Alexis Bañuelos Díaz

doi:10.16925/in.v13i22.1750

Use of Reversed-Phase hplc for the Determination of Free Formaldehyde Content in Nail Polishes

Investigación

https://doi.org/10.16925/in.v13i22.1750

María Maldonado Santoyo Ver Biografía

Centro de Innovación Aplicada en Tecnologías Competitivas (CIATEC),

Erika Hernández Guerrero Ver Biografía

Universidad de Guanajuato

Gladys Morales López Ver Biografía

Universidad Politécnica del Bicentenario

Javier Antonio Arcibar Orozco Ver Biografía

Investigador del Centro de Innovación Aplicada en Tecnologías Competitivas (CIATEC)

Juliette Alexandra Lambert Ver Biografía

Investigador del Centro de Innovación Aplicada en Tecnologías Competitivas (CIATEC)

Jennifer Alexis Bañuelos Díaz Ver Biografía

Investigador del Centro de Innovación Aplicada en Tecnologías Competitivas (CIATEC)

Introduction: This article derives from the research titled Use of reversed-phase hplc for the determination of free formaldehyde content in nail polishes, conducted in 2015 at the Center for Applied Innovation in Competitive Technologies (ciatec).

Method: The free formaldehyde content was determined in 50 samples of nail polishes of various brands marketed in León, Guanajuato, Mexico. Samples were treated according to the iso 17226-1:2003 method, with slight modifications: 2 ± 0.1 g of nail polishes were weighed in 100 ml Erlenmeyer flasks, 40 ml of 0.1 % sodium dodecyl sulfonate were added; the samples were then capped and left in a water bath at 40 °C under constant stirring for 60 minutes; they were subsequently filtered, and aliquots of each sample were taken for derivatization with 0.3 % 2,4-dinitrophenylhydrazine for 60 minutes. The analytical determination was achieved by reversed-phase hplc-diode array detection.

Results: All nail polish samples tested were below the regulatory limit of 0.2 % free formaldehyde content in cosmetics.

Conclusions: We obtained toxicologically relevant information on free formaldehyde in nail polishes, in addition to checking the versatility and robustness of the test method.

Keywords: HPLC, DNFH, nail polish, formaldehyde

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M. Maldonado Santoyo, E. Hernández Guerrero, G. Morales López, J. A. Arcibar Orozco, J. A. Lambert, and J. A. Bañuelos Díaz, “Use of Reversed-Phase hplc for the Determination of Free Formaldehyde Content in Nail Polishes”, ing. Solidar, vol. 13, no. 22, pp. 27–37, May 2017, doi: 10.16925/in.v13i22.1750.

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Vol. 13 No. 22 (2017)

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2017-05-01

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